Silvia Colombini was born in Rome into a famous Italian musical family who include the composer Giancarlo Colombini ( and singers as  Edoardo Camera (known famously as Puccini's baritone), Giuseppe Bellantoni and Roberto Stagno.

After graduating with a diploma in violin and in opera singing, following the suggestion of Edita Gruberova, Silvia studied in Wien under Ruthilde Boesch, who was famously Gruberova's teacher. It was at this time that she won three international singing  competitions. In 1999 she made her debut in Wien in the role of Adele in J.Strauß's ”Die Fledermaus’.
Silvia sings in English, German, Italian, French, Czech, Russian, Chinese. 
She speaks English and German.
Up to date Silvia has sung in more than 400 performances in the most important Italian and International opera houses. As a Light Lyric Coloratura Soprano, her opera credits include: La Sonnambula (Bellini Theatre in Catania) Elisir d’amore (Köln Opera, New Israeli Opera) Un ballo in Maschera (Arena di Verona) Don Pasquale, Rigoletto, Bohème, in some new productions; Lakmé (Massimo Theatre in Palermo).
Critically acclaimed as an exceptional Mozart interpreter, her Mozart operatic credentials include: Blonde, Die Entführung aus dem Serail (Dresden Semperoper Theatre, Teatro Regio in Turin, Petruzzelli Foundation in Bari) Queen of the Night, Die Zauberflöte (Dresden Semperoper Theatre, Berlin Staatsoper, Köln, Frankfurt, Bonn Opera Theatres) Despina, Così fan tutte (São Carlos Theatre in Lisbon, Mozart Festival in La Coruña) Elisa, Re Pastore (Royal Theatre de La Monnaie in Brussels).
Invited by the Salzburg Festival to sing in the opera ,‘Die Ägyptische Helena’,  Silvia was then invited to sing in ‘Die Frau ohne Schatten’ for the Opening Night of the 73rd Maggio Musicale Fiorentino Festival, conducted by Zubin Mehta.  
Silvia has performed one of the most difficult roles ever written for Soprano: Cordelia (A. Reimann's Lear) at the Teatro Regio in Turin (director: Luca Ronconi) and at the Dresden Semperoper Theatre (director: Willy Decker).
On the recital stage Silvia has given concerts at Bayerischer Rundfunk in Munich, Mitteldeutscher Rundfunk, Gewandhaus in Leipzig, Gasteig Hall, Auditorium Parco della Musica in Rome, Sala Nervi in the Vatican (for the Pope John Paul II), Quirinale of Rome (at the presence of the past Italian Republic President) Mehli Metha Music Foundation in Bombay. These concerts included a full cross section of repertoire including: sacred music, opera, lieder, art song and crossover. 
In September 2012 Silvia gave a concert for Festival MITOSettembremusica in Milan and was the guest soloist for the New Year's Gala 2013 at the historical 'Teatro Bellini' in Catania.
She has taken part in two Japanese tours; these included all of the most important Japanese opera houses (among them: Tokyo Bunka Kaikan) and every year she is invited to sing in a national concert tour of China. She has performed in 14 cities, among them  Shanghai  at the Shaghai Concert Hall. 
In 2013 Silvia began a collaboration with the chamber ensemble 'Limes Ensemble' ( with whom she has performed on tour in China and Africa.  
As a  crossover artist Silvia has presented concerts in collaboration with the Jazz pianista Danilo Rea. With Rea and the artist 'Martux' she has also recorded the CD ‘Reminescence’  (Parco della Musica Records).
Silvia has worked with the following conductors and directors: M. Horvat, Z. Mehta, F. Luisi, Z. Pesko, S. Ranzani, D. Renzetti, M. Viotti, O. Dantone, T. Netopil, O. Meir Wellber; L. Ronconi, M. Martone, C. Lievi, D. Livermoore, B. de Tommasi, F. Crivelli, J. Schaaf, W. Decker, E. Gramss.
As a teacher Silvia has created an innovative singing method translated as the “Art of Resistance Surpassed – A.R.S -C” which she presented at Shanghai's Tonji University in 2011.